Endocrine Abstracts

Introduction: Today simultaneous pancreas-kidney transplantation (SPKT) is an effective method of treatment for patients with type 1 diabetes mellitus (T1D) and terminal stage of diabetic nephropathy (DN) on renal replacement therapy by hemodialysis. It solves several problems: reduces the severity of intoxication syndrome, contributes to the achievement of euglycemia in most cases, that allows to delay progression of micro- and macrovascular diabetic complications. Case Descr...

Objective: To evaluate the impact of different modes of insulin therapy (continuous subcutaneous insulin infusion (CSII) using insulin pump or multiple insulin injections (MII)) on carbohydrate metabolism, the state of the transplant, cardiovascular system, calcium and phosphorus metabolism in patients with type 1 diabetes (DM1) during the 1st year after kidney transplantation (KT).Materials and methods: The study included patients with DM1 after transpl...

Objective: To evaluate the simultaneous pancreas–kidney transplantation (SPK) effect on stabilisation/progression of complications in patients with T1DM.Materials and methods: The study included 16 patients after SPK. Eleven peoples received standard triple immunosuppressive therapy during the study period, five patients canceled steroid therapy after 6 months. The average age was 34 years old (31; 40), duration of T1DM 22 years (20.5; 28), the dura...